Using a topical treatment that blocks DHT is one way to help your body fight this problem. In addition to prescription medications, you can also use a variety of natural products, such as Saw palmetto, Biotin, Rosmarinus officinalis leaf extract, and Finasteride. These treatments are not right for everyone, though, so we’ve listed some of our favorites below. Read on to find out which one is right for you.
Biotin blocking DHT topically by preventing its production. This ingredient has a variety of applications, including shampoos, conditioners, and topical serums. Using these products on the scalp will help to promote hair growth. This natural ingredient is also found in certain foods, including pumpkin seed oil and white mushrooms. These substances contain phytosterol and lycopene. Biotin is also present in oily fish, bananas, and liver.
Biotin is a cofactor for carboxylase enzymes, which activate when joined by an enzyme called holocarboxylase synthase. This enzyme complex is involved in multiple metabolic processes, including fatty acid synthesis and amino acid catabolism. Biotin is widely available in foods, and is particularly abundant in nuts, whole grains, unpolished rice, and egg yolk. But before using biotin supplements, talk to your doctor.
Rosmarinus officinalis leaf extract
Research has shown that R. officinalis leaf extract reduces DHT levels in the blood. This ingredient is known for its unpleasant sting when touched with the bare hands. It is an effective DHT blocker when applied topically to the scalp and is believed to reduce symptoms of prostate hyperplasia and enlargement. However, the effectiveness of nettle root has not been replicated in other studies.
Topical application of this herb can also increase the growth of hair. It has been shown to increase capillary blood circulation, which benefits hair follicle nutrition. A topical application of R. officinalis leaf extract inhibits the conversion of 5aR by 82.4%. The herb also stimulates hair regrowth in C57BL/6NCrSlc and C3H/He mice. The inhibitory action of R. officinalis leaf extract on testosterone levels has also been identified as a potential treatment for androgenic alopecia.
One study aims to discover whether Finasteride blocks DHT in males by topical application. The study used 450 patients randomized in a 2:1 allocation ratio. The study allowed for 20% attrition. A total of 144 patients were needed for the topical finasteride arm, while a similar number were randomized to the placebo arm. The primary endpoint was a reduction of serum DHT levels. The lower limit of quantification for both treatments was 4 pg/mL.
Despite the risks of side effects, topical DHT blockers are less effective than oral drugs. Moreover, they have fewer systemic side effects. This makes topical treatment a good option for those who have experienced side effects from oral DHT blockers. While reducing the DHT level in the bloodstream is an effective way to treat alopecia, hair loss can be prevented by targeting the hair follicle. Finasteride blockers are effective in blocking DHT before it can cause damage.